Race Against Time: The Crumbling Garden Shed Where Jenner Pioneered Vaccines
Jenner's vaccine shed declared at risk

The modest garden shed in Gloucestershire where Edward Jenner made medical history by administering the world's first vaccinations now faces its own battle for survival. This unassuming structure, known as the Temple of Vaccinia, has been officially placed on Historic England's Heritage at Risk Register for 2025.

The Birthplace of Immunology

Nestled in the garden of Jenner's former home in Berkeley, this simple wooden hut witnessed one of medicine's greatest breakthroughs. It was here in 1796 that Jenner conducted his pioneering smallpox vaccination experiments, laying the foundation for modern immunology and ultimately saving countless millions of lives worldwide.

The shed's significance cannot be overstated - it represents the very spot where humanity began its successful fight against one of history's deadliest diseases. Smallpox, which once killed approximately 30% of its victims, was officially declared eradicated in 1980 thanks to vaccination programmes stemming from Jenner's work.

A Structure in Peril

Despite its global importance, the Temple of Vaccinia now shows significant signs of deterioration. Historic England has identified concerning structural issues including:

  • Weather damage to the wooden construction
  • Foundation instability
  • General decay from age and exposure
  • Urgent need for specialist conservation

The building's inclusion on the at-risk register highlights the immediate threat to its preservation and the urgent need for intervention.

Preserving Medical Heritage

The Jenner Trust, which manages the site, has expressed both concern and determination regarding the shed's future. "This isn't just about preserving old wood and nails," explained a trust representative. "We're safeguarding the physical embodiment of one of medicine's most important moments. When people stand where Jenner stood, they connect directly with that revolutionary breakthrough."

Conservation efforts will require specialist expertise and significant funding to ensure the shed's survival for future generations. The trust aims to undertake careful restoration that maintains the building's authentic character while securing its structural integrity.

Global Significance, Local Treasure

While the shed holds importance for the global medical community, it remains a cherished part of Gloucestershire's local heritage. Visitors from around the world make pilgrimages to the site, drawn by its unique place in medical history.

The conservation project represents not just the preservation of a building, but the protection of a site that changed human health forever. As vaccination continues to play a crucial role in modern medicine, saving this humble shed ensures we remember where it all began.