Dr Jiri Kubes, a radiation oncologist and medical director at the Proton Therapy Center in Prague, warns that many people overlook subtle signs of cancer, attributing them to stress, aging, or minor illnesses. With over 403,000 people diagnosed with cancer each year in the UK—equivalent to 1,100 daily or one person every 80 seconds—early detection is crucial.
Commonly overlooked symptoms
Dr Kubes emphasizes that cancer does not always present dramatic symptoms. Instead, vague and persistent changes may be the first clues. He urges people to pay attention to symptoms that linger, recur, or feel unusual for them, even if they seem minor.
Persistent fatigue
While tiredness after a busy week is normal, fatigue that does not improve with rest and interferes with daily activities is a red flag. Dr Kubes explains: 'Cancer-related fatigue is often described as an overwhelming exhaustion that doesn’t improve with sleep.' Other causes include anaemia, thyroid disorders, and infections, but persistent fatigue warrants a GP visit.
A cough that won’t go away
A cough from a cold or viral infection typically resolves within a few weeks. If it persists or worsens, it may signal something more serious. Dr Kubes notes: 'A persistent cough doesn’t automatically mean cancer,' but if accompanied by breathlessness, chest pain, or coughing up blood, urgent medical help is needed.
Unexplained weight loss
Losing weight without changes in diet or exercise can be an early sign of cancer. 'If you’re losing weight despite eating normally and haven’t intentionally changed your lifestyle, it’s important to understand why,' says Dr Kubes. While other explanations are possible, it should not be ignored.
Dr Kubes concludes: 'The important thing is persistence. If something continues for several weeks, keeps returning or simply doesn’t feel right for you, it’s always worth getting checked rather than assuming it will eventually go away.'



